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1.
为保障动物源性食品安全、加强农业投入品的质量安全监管.实施农业部和市农业局下达的饲料、兽药、畜产品残留监测计划.重庆市兽药饲料检测所召开专题会议.安排部署2008年度饲料、兽药及畜产品残留监测工作。从2月20日起,重庆市兽药饲料检测所陆续派出技术人员到各区县进行饲料、兽药及畜产品抽样,拉开了全市饲料、兽药及畜产品抽样监测工作序幕。  相似文献   

2.
畜产品安全主要包含2个方面,一方面是动物疫病,另一方面是畜产品中的有毒有害物质。畜产品中的有毒有害物质主要包括重金属及药物残留。本文就我国畜产品质量安全标准及国内外药物残留的监控状况作一简述。1畜产品质量安全标准我国对畜产品安全比较重视。1991年,国务院办公厅就以国办发[1991]67号《关于加强农药、兽药管理的通知》提出了加强兽药及兽药残留管理的要求。根据国务院的分工,农业部负责制订兽药在动物性食品中的最高残留限量。1994年,农业部以农(牧)字第5号文发布了42种兽药在动物性食品中的最高残留限量。3年后,农业部又以农牧…  相似文献   

3.
畜禽养殖产业的快速发展也导致养殖中的疾病问题开始逐渐凸显,防治畜禽养殖中疾病兽药的使用量也不断提高,兽药的不规范使用易导致残留的情况,对于畜产品中兽药的残留问题受到广泛的关注。畜产品中兽药的残留会影响畜产品的质量,对消费者的机体健康带来负面影响,同时部分兽药的残留会导致生态环境的污染,进而影响人类健康。该文对畜禽养殖中畜产品兽药残留出现的原因,造成的危害及改进和防控措施进行论述。  相似文献   

4.
笔者从事兽药质量、饲料质量、畜产品中兽药残留检测及管理十多年.在畜产品质量安全方面积累了一定经验,为此,深入分析了南阳市畜产品安全现状和存在问题,并提出了一些有针对性的解决办法和建议以供参考。  相似文献   

5.
兽药残留是影响动物性食品质量安全的重要因素,本文通过分析兽药残留带来的危害以及兽药残留对畜牧业发展的危害,探索性的提出了相应的控制措施。旨在通过有效的监管和控制措施的实施,从源头上杜绝或减少畜产品的兽药残留,达到促进畜牧业健康发展,确保畜产品质量安全。  相似文献   

6.
《兽医导刊》2008,(3):65-65
为保障动物源性食品安全、加强农业投入品的质量安全监管,实施农业部和重庆市农业局下达的饲料、兽药、畜产品残留监测计划,重庆市兽药饲料检测所召开专题会议,安排部署2008年度饲料、兽药及畜产品残留监测工作。  相似文献   

7.
兽药是畜禽养殖主要的投入品,也是决定畜产品质量安全的关键因素。近几年,兽药残留事件、"瘦肉精"事件、"三聚氰胺"等事件的发生,严重危害消费者健康。在养殖过程中,由于兽药等投入品的不合理使用,会造成畜产品药物残留及有害物质超标,从而影响畜产品质量安全。合理使用兽药,加强兽药使用监管事关畜牧业的健康发展,事关人民群众的身体健康。因此,兽药的使用在畜禽养殖过程中非常重要。  相似文献   

8.
规范用药是防止畜产品药物残留超标,提高畜产品质量和国际竞争力以及预防医疗事故发生的最根本的措施。规范用药范围甚广,现就农村养殖中在使用兽药中存在的几个主要问题和几种规范用药的方法进行介绍,供参考。一、严格执行国家兽药法规近几年,国家鉴于饲料中兽药含量过高,兽药本身质量低劣和盲目大剂量滥用兽药,畜产品中药物残留超标、质量有所下降的问题,全国人大常委会、国务院等国家有关部门陆续颁布了《中华人民共和国动物防疫法》、《饲料和饲料添加剂管理条例》、《兽药管理条例》、《兽药典》、《兽药规范》、《兽药质量标准》、《…  相似文献   

9.
绿色、无残留动物性食品亟待中兽药市场开发   总被引:3,自引:0,他引:3  
随着各种兽药的频繁使用,动物性食品中的兽药残留越来越多。主要针对畜产品质量安全一题展开讨论.阐述了动物性食品中兽药残留的来源、危害,以及中兽药的研发前景。  相似文献   

10.
为贯彻落实《食品质量安全法》和《农产品质量安全法》,确保畜产品质量安全,新疆维吾尔自治区昌吉回族自治州畜产品质量检测中心开展了畜产品质量安全监督检测工作。检测样品包括肉、奶、蛋等食用畜产品及兽药、饲料、饲料添加剂等投入品,抽样对象主要是养殖场户、屠宰场、生鲜乳收购站、运输车、市场散奶、农贸批发市场等,检测指标主要是国家明令禁止的兽药残留、农药残留、污染物、违禁添加物及常规营养成分等。  相似文献   

11.
The tissue distribution and residue profile of diminazene aceturate was investigated in healthy dogs and in dogs infected with Trypanosoma congolense and Trypanosoma brucei brucei. The drug was administered at 3.5 mg/kg i.m. and tissue samples were taken post mortem from the animals at 48, 72, 120, 168 and 240 h after injection. The drug was distributed to various organs and tissues of the body with the highest concentrations occurring in liver and kidney. Higher drug levels were obtained in the tissues of healthy dogs compared with trypanosome infected animals except in the brain. The levels of residues in the healthy animals were significantly different (P less than 0.05) from those of the infected dogs. The drug residues were still detectable in the tissues of the animals 10 days after drug administration.  相似文献   

12.
动物源食品中多种兽药残留主要是动物在生长和加工中额外添加。该种残留现象具有水平低、种类多、机制效应复杂的特点。针对该种动物制品在进行兽药残留检测中应综合运用新技术新方。目前在动物源食品中多种兽药残留检测中常用的技术为高效液相色谱质谱联合使用技术,该项技术具有检测灵敏度高,数据获取精准的特点,能对多种兽药残留情况进行定性定量的分析,在动物源食品多种兽药残留检测过程中应用较为广泛。该文主要论述动物源食品中多种兽药残留的种类及兽药残留检测技术。  相似文献   

13.
Residual antimicrobials in food constitute a risk to human health, but poor knowledge is available about the significance of contaminated meat in developing countries. The purpose of the study was to determine the occurrence of antimicrobial drug residues in pork products in Madagascar. The occurrence of antimicrobial drug residues in pork meat were investigated by the Premi® test (DSM©) technique. There was a high incidence rate of drug residues, with 360 (37.2 %) meat samples being contaminated. A significant increase was observed between 2010 and 2011, with 32 and 39%, respectively. Pork meat samples are less contaminated by drug residues when animals are slaughtered in urban abattoirs (34.4%) vs in provincial abattoirs (42.2%), suggesting that animals under treatment (or sick) are sold preferentially in local abattoir. Drug residue levels in pork meats purchased in Madagascar appear to be serious public health problem at the moment.  相似文献   

14.
抗球虫药物在畜禽业应用广泛,可预防治疗球虫病,提高家禽饲料转化率,提升肉品质。但是,随即会出现饲料交叉污染,对非目标动物产生毒性作用,动物性食品中药物残留超标等问题。因此,建立简便、快速、灵敏度高的检测方法检测动物源性食品中的抗球虫药物残留极为重要。基于抗原-抗体特异性结合原理的免疫分析检测技术能够完成快速检测,高通量筛选,具有特异性强、灵敏度高、操作简便、成本低的优点。本文综述了不同基质中抗球虫药物残留的免疫检测技术进展,重点介绍了酶联免疫吸附检测法、免疫层析法、荧光偏振免疫分析检测法、时间分辨荧光免疫分析检测法和生物传感器检测法。并对免疫检测技术在残留检测方面的发展趋势进行了展望,旨在为抗球虫药物的残留监控提供方法学上的参考,为新方法的建立提供思路。  相似文献   

15.
Healthy gilts and market-ready hogs were administered a single intramuscular (IM) injection of Borgal, a commercial formulation of trimethoprim-sulfadoxine (TMP-SDX), once or twice daily. The objectives were to determine if a newly-developed high-performance liquid chromatographic (HPLC) method would be suitable for measuring the residual concentrations of TMP in the plasma of these live animals, and to determine if the administration of this veterinary drug would leave measurable residues in their plasma and tissues at slaughter. Plasma and tissue concentrations of SDX and TMP from these animals were determined over a period of 14 d using thin-layer chromatography/densitometry (TLCD), and the newly-developed HPLC method, respectively. The lowest detectable limit (LDL) for SDX in plasma and tissue was 20 ppb by TLCD. The HPLC method had a LDL of 5 ppb for TMP in plasma and tissue. Both methods were then used to provide baseline data on the absorption and depletion of TMP and SDX from these healthy animals. It was observed that both TMP and SDX were readily absorbed into the blood and tissues, but TMP was eliminated much faster than SDX. No TMP residues were detected in the plasma of any of the gilts at and beyond 21 h after drug administration. Also, no TMP residues were detected in the plasma of any of the market-ready hogs 24 h after drug administration at either the label dose or twice the label dose. Sulfadoxine residues at concentrations above the maximum residue limit (MRL) of 100 ppb were, however, detected in the plasma, muscle, kidney, liver, and injection sites of hogs slaughtered 1 and 3 d after a single IM administration at the label dose. Although SDX residues were still detectable in the lungs, kidney, liver and plasma of some hogs 10 d after administration of the label dose and twice the label dose, these were below the MRL. Postmortem examination revealed necrosis and inflammation at the injection sites, but no visible deposits of the injected drug.  相似文献   

16.
The administration of antimicrobial agents to livestock creates potential for antibiotic residues to enter the food supply and be consumed by humans. Therefore, as a process of food animal drug registration, national regulatory agencies and international committees evaluate data regarding the chemical, microbiologic, pharmacokinetic, pharmacodynamic, pharmacologic, toxicologic, and antimicrobial properties of veterinary drugs to assess the safety of ingested antimicrobial residues to consumers. Currently, European, Australian and United States guidelines for veterinary drug registration require a safety assessment of microbiologic hazards from consumption of antimicrobial residues taking into account the potentially adverse effects on human intestinal microflora. The main concerns addressed are selection of resistant bacteria in the gastrointestinal tract and disruption of the colonization barrier of the resident intestinal microflora. Current requirements differ among national agencies. Efforts are ongoing internationally to review and harmonize approaches and test methods and protocols for application to these microbiologic safety evaluations of antimicrobial drug residues in food. This review describes the background to current regulatory approaches used in applying in vitro and in vivo methods to set a microbiologic acceptable daily intake for residues in food derived from animals treated with an antimicrobial agent. This paper also examines the current research needs to support these evaluations.  相似文献   

17.
 随着兽药和药物添加剂在畜禽饲养过程中长期不合理的使用,残留在动物体内的兽药及其添加剂随着食物链进入人体,对人类的健康构成潜在威胁。加强对兽药残留的检测,对保护生态环境和人类的身体健康有着极其重要的现实意义。近年来,液相色谱—串联质谱技术以其良好的适用性、定性定量功能及高灵敏度等优点,在兽药残留的检测方面已得到了广泛应用。论文概述了液相色谱—串联质谱技术在饲料、畜产品和尿液中兽药残留以及违禁药物和有害添加剂检测的应用现状。  相似文献   

18.
There are a number of factors that must be considered in any attempt to control animal drug residues in milk and milk products. Dairy herds vary greatly in number of cows. Milk from individual cows and farms is pooled, diluting drug residues that may be present in the milk from a single treated cow. Management techniques, including the handling, administration, and record keeping of animal drugs, vary greatly from one dairy to another. It is important that both veterinarians and nonveterinarians adhere to adequate milk discard times for animal drugs used to treat dairy animals. Observance of appropriate safeguards at the farm level, such as record keeping and clearly identifying treated animals, is critical for controlling and preventing the presence of illegal animal drug residues. Within the framework of the Federal Food, Drug, and Cosmetic Act and the Public Health Service Act, the FDA is working with state and other regulatory agencies and industry to better ensure the absence of illegal animal drug residues in milk and milk products. Preventive measures concentrate on minimizing the need to administer animal drugs to lactating cows, and diverting milk containing drug residues from the human food supply. Monitoring programs concentrate on screening milk and tracing violations to the individual producer. Minimizing illegal drug residues in milk and milk products requires close cooperation between farmers, veterinarians, the dairy industry, the pharmaceutical industry, and regulators.  相似文献   

19.
Drug residues in food animals   总被引:5,自引:0,他引:5  
A total of 292 field investigative reports of drug residues in food animals for 1983 to 1988 were analyzed. The investigations had been conducted by the Food and Drug Administration (FDA) and the Virginia State Veterinarian's Office, in cooperation with the Center for Veterinary Medicine of the FDA, to trace residues reported by the USDA Food Safety and Inspection Service to the source of the animal and the administration of the drug. The analysis disclosed the following. (1) Antibiotic residues were most often associated with streptomycin, penicillin, oxytetracycline, and neomycin. Sulfamethazine was, by far, the most frequently cited sulfonamide. (2) Residues are being found predominantly in cows, veal calves, and market hogs (barrows and gilts). (3) The cause of drug residue most frequently cited by the field investigators was failure to observe the withholding time for the drug. Almost half of these investigations revealed that the individual responsible for the sale of the animal did not know the proper withholding time for the drug. Failure to maintain adequate records was also a contributing factor. (4) The producer was considered to be the responsible party in over 80% of the cases for which responsibility was determined. (5) Residues associated with injectable drugs were investigated most frequently. Long-acting and sustained-release products were most often associated with penicillin and oxytetracycline residues. (6) The 2 most common sources of purchase for the drugs involved in the investigations were the feed/farm supply store and the veterinarian. (7) Unapproved drug use was not a major cause of residues.  相似文献   

20.
A single oral dose of oxytetracycline hydrochloride (50 mg/kg) produced detectable residues in the following tissues; adrenal, bile, fat, heart, kidney (cortex), kidney (medulla), liver, lung, lymph node (mesenteric), muscle, serum, spleen, thyroid and urine. The highest residue levels were observed in the urine (441 μg/mL) at three hours after administration and they were still present at 48 hours. Maximum serum levels were observed at two hours after administration. Bile samples were positive for inhibitors in all animals sampled. Drug residues were not detected in spleen, thyroid, lymph node, adrenals and heart at 48 hours.

Drug levels in important edible tissues were expressed as a percentage of drug levels in two tissues with high drug concentrations — urine and kidney cortex. The percentages were highly variable when compared with urine and much less variable when compared to kidney cortex.

Kidney cortex appears to be an excellent tissue for drug residue monitoring.

  相似文献   

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