猪传染性胃肠炎科学预防与治疗

随着人们生活水平的不断提高,人们对猪肉产品品质要求越来越高、需求量越来越大,特别随着生猪养殖业的养殖模式向着规模化、集约化方向转变,在生猪养殖过程中疾病的发生会对养殖场的经济造成严重的损失。猪传染性胃肠炎的传播及流行成为生猪养殖场难以预防疾病之一,会影响猪只断奶生长发育,猪群感染该病后死亡率很高,该病的发生会造成生猪养殖业的发展受阻。猪只感染该病后猪只会表现出肠炎、呕吐、腹泻、脱水等症状,若是养殖场没有对患病猪只及时进行治疗,会导致该病的死亡率增多。对此要加强对猪传染性胃肠炎的预防及治疗,就需要了解猪传染性胃肠炎的流行特征、临床症状及病理变化,并根据猪传染性胃肠炎的发病原因提出科学有效的防治措施,以降低养殖场猪传染性胃肠炎的发病率,保证生猪的健康发展,进而促进养殖场的健康发展。     

猪传染性胃肠炎的正确治疗

在生猪养殖过程中,猪传染性胃肠炎是一种急性的接触性传染病,感染此种疫病的生猪具有较高的死亡率,且伴随着强烈的传染性,一旦暴发猪传染性肠胃炎,轻度疫区的患病猪生长速度会降低,而重度疫区的生猪则会成片的死亡,给广大养殖户造成经济损失,因此养殖户要树立归于该疫病的预警机制,一旦出现类似患病情况应当及时通过科学的方式进行治疗,进而保证养殖收益.     

猪传染性胃肠炎的防治策略

正猪传染性胃肠炎作为急性胃肠道感染性疾病,是生猪在养殖过程中多发的疾病,其症状表现为腹泻、呕吐,严重将会导致病猪脱水死亡,因此,对养殖户造成严重损失。这一情况下,养殖户要加强养殖过程中的防治,从而有效预防感染以及提升经济效益。1流行特点猪传染性胃肠炎是生猪在养殖工程中较为常见的一种传染性疾病,无论是危险程度还是影响程度都很高。对于生猪而言,任何生长时期都会存在感染传染性胃肠炎的发生几率,特别是仔     

猪传染性胃肠炎的症状和防治措施

猪传染性胃肠炎是由猪传染性胃肠炎病毒引发的一种急性、高度接触性、胃肠道传染病,此病在生猪养殖过程中对猪的健康生长影响很大,只要稍有不慎,传染性胃肠炎就会在很短的时间内传播到整个猪群,造成猪的腹泻、消瘦、脱水,甚至猪的死亡。笔者通过长期工作与摸索,积累了一定的经验,将对生猪养殖过程中传染性肠胃炎出现的发病原因,疾病症状以及相关的治疗措施进行阐述,旨在为生猪的健康养殖带来帮助。     

猪常见传染病的治疗

正作为目前养猪常见的疾病类型之一,猪的传染性疫病也是危害其生长的重要因素。在生猪的养殖过程中由于自然环境和养殖技术条件的制约,猪会感染上多种类型的疫病。对此,在养殖中必须采取必要手段对疫病加以防治。1猪常见传染性疫病及其发病原因生猪染病的风险因素很多,有环境因素、养殖人员不合理的用药及免疫剂量不足因素,也有猪自身抵抗力低的原因。常见猪传染性疫病主要有猪传染性胃肠炎、猪瘟、猪丹毒及猪接触传染性胸膜性肺炎。猪传染性胃肠炎是由胃肠炎     

猪传染性胃肠炎的兽医治疗

传染性胃肠炎是生猪较为高发的一种疫病,多高发于冬春季节。生猪一旦感染该病,就会出现腹泻、呕吐等症状,严重时甚至会出现死亡,而这必然会对生猪养殖效益造成损失。基于此,本文笔者主要从猪传染性胃肠炎的病原、流行病学、临床症状、实验室诊断及兽医防治展开探讨,以供广大生猪养殖人员参考。     

夏季猪病毒性腹泻的防治

在生猪养殖过程中,病毒性腹泻是较为常见的一种疾病,病死率较高,一旦发生会给生猪养殖产业造成直接影响。夏季是猪病毒性腹泻的高发期,因而在夏季做好猪病毒性腹泻的防治工作尤为重要。1猪常见病毒性腹泻病的特点1.1传染性胃肠炎传染性胃肠炎是养猪过程中较为常见的一种高度传染性肠道传染病,该病的病原为冠状病毒。病猪的体液、器官以及粪便内可见病毒。病猪常常会感染健康猪只,尤其在密闭的猪舍内该病传播速度极快。     

传染性胃肠炎在猪养殖中的防治分析

传染性胃肠炎是生猪养殖中的常发性疾病,其不仅会影响到生猪的正常生长以及生命安全,亦会出现大规模的感染,造成巨大的经济损失,对于规模化的生猪养殖厂影响甚重.本文就如何做好传染性胃肠炎在生猪养殖中的防治工作作一简单的探索分析,以期为相关生猪养殖户提供相应的参考.     

生猪传染性胃肠炎发病原因及防治措施

作为生猪养殖过程中发病率较高的一种疾病,猪传染性胃肠炎通常是由冠状病毒感染引起,该病具有较强的传染性,主要发生于小于2月龄的仔猪,会对10日龄内的仔猪造成极高的死亡率。近年来,猪传染性胃肠炎的发病率逐渐提升,因而有必要对该病的发病原因进行深入的研究,并探寻出有效的防治措施。     

猪传染性胃肠炎临床诊断及防治

当前,在我国畜牧养殖行业当中,生猪养殖十分重要,不仅可以带动地区经济的发展,也与人们的日常生活息息相关。在生猪养殖中,受到多方面因素的影响,难免出现一些传染疾病,其中,传染性胃肠炎十分常见。生猪在患上传染性胃肠炎之后,容易出现死亡,且如果无法进行防治、控制,容易出现大面积扩散。所以,对猪传染性胃肠炎进行科学的诊断、做好防治工作十分关键。     

Transmissible gastroenteritis: demonstration of the virus from field specimens by means of cell culture and pig inoculation.

Isolation of transmissible gastroenteritis virus was attempted from segments of jejunum collected from piglets submitted for diagnosis of transmissible gastroenteritis. The virus was isolated more frequently in susceptible piglets than in pig kidney or pig thyroid cells. Practically, both cell systems were equally capable of demonstrating the virus when the tissue suspensions were sonicated. The pig thyroid cells prepared with glands collected from minimal disease pigs were preferred to the pig kidney cells for initial virus isolation because of their ability to respond to transmissible gastroenteritis virus with a progressive cytopathic effect. However, the pig thyroid cells, prepared from pool of glands collected in abattoirs, were often contaminated with parvoviruses and could not be used for diagnostic work. Controlled ultrasound treatments of the inoculum increased the frequency of virus isolation in both cell systems.     

猪传染性胃肠炎药物治疗研究进展

猪传染性胃肠炎对养猪业的危害很大,对于该病除采用疫苗预防之外,进行临床上的药物防控也不容忽视,因为目前疫苗预防方面也存在着一定的问题.临床上对猪传染性胃肠炎的治疗有较多的报道,有中药复方制剂治疗方面的尝试,也有根据临床腹泻症状进行西药治疗,还有中西药相结合进行治疗.这对于临床防控猪传染性胃肠炎不仅提出了许多可以借鉴的方法,也为临床防治猪传染性胃肠炎提供了思路.     

中草药防治猪传染性胃肠炎的研究进展

猪传染性胃肠炎是由猪传染性胃肠炎病毒引起的一种高度接触性肠道疾病。该病不仅可导致不同品种和各生长期的猪产生呕吐、腹泻和失水等临床症状,还具有传染性强、传播速度快的特点。因此,为了使猪传染性胃肠炎病得到有效的防治,文章主要从猪传染性胃肠炎的危害概况、中草药在猪传染性胃肠炎防治中的应用概况、中药防治猪传染性胃肠炎作用机理3个方面探讨了当前中草药防治猪传染性胃肠炎的研究进展,以期为兽医临床防治猪传染性胃肠炎提供理论依据。     

An outbreak of diarrhea in piglets caused by a coronavirus antigenically distinct from transmissible gastroenteritis virus

Coronavirus-like particles were visualized by electron microscopy in the intestinal contents of piglets during a diarrheal outbreak on a Quebec pig farm. The precipitating antigens of transmissible gastroenteritis virus were not detected in the intestinal contents of diarrheic animals by counter-immunoelectrophoresis. Insignificant antibody titers against transmissible gastroenteritis virus were demonstrated in the sera of convalescent pigs by indirect immunofluorescence and these sera did not react with transmissible gastroenteritis virus when tested by immunoelectron microscopy. The causative agent could not be isolated in cell cultures. It was concluded that a coronavirus antigenically distinct from transmissible gastroenteritis virus was responsible for the enteric problems observed on this farm. The outbreak was controlled after oral inoculation of adult pigs with infected intestinal contents.     

Direct immunoelectron microscopy of transmissible gastroenteritis virus with immunoglobulins G and A and guinea pig complement

Porcine colostral immunoglobulin (Ig)G and IgA, isolated from transmissible gastroenteritis virus-infected sows, were compared by direct immunoelectron microscopy. It was estimated, using antibodies with a less than a twofold difference in virus-neutralizing activity, that IgG was 500 times more efficient than was IgA for coating transmissible gastroenteritis virions. Guinea pig complement enhanced the antibody coating with IgG, but did not increase virus-neutralizing activity of IgG or IgA.     

Use of monoclonal antibodies in blocking ELISA detection of transmissible gastroenteritis virus in faeces of piglets

Monoclonal antibodies (mAb) to the transmissible gastroenteritis virus (TGEV) nucleoprotein (N) and membrane protein (M) were prepared and used for the comparative assessment of three blocking ELISA variants to detect TGEV. The competitive blocking ELISA format showed the highest sensitivity, allowing detection of 10(3) TCID50 TGEV/ml in culture medium. Ninety-nine porcine field faecal samples obtained from 37 herds affected with diarrhoea were examined, and various TGEV levels were found in nine samples from six herds. However, only in three samples were significant TGEV concentrations demonstrated. The relationship between incidence of TGEV gastroenteritis and the spread of porcine respiratory coronavirus infection in pig farms is discussed.     

Transmissible gastroenteritis in endemically infected breeding herds of pigs in East Anglia, 1981-85

Endemic infection was a common sequel to primary outbreaks of transmissible gastroenteritis in large breeding herds of pigs in East Anglia. The main clinical features of the disease were diarrhoea affecting sucking piglets aged about six days or more, diarrhoea among recently weaned pigs and brief episodes of overt clinical recrudescence in part of the herd. Post mortem and bacteriological findings were often more suggestive of colibacillosis than transmissible gastroenteritis. In some herds, endemic infection remained clinically mild or inapparent for long periods. Evidence of endemic transmissible gastroenteritis infection was found in 43 (50.6 per cent) of 85 herds of pigs studied prospectively between 1981 and 1983. There was a significant correlation with herd size; the disease recurred during the 12 months after primary outbreaks in 36 (65.5 per cent) of 55 herds with over 100 sows compared with seven (23.3 per cent) of 30 herds with less than 100 sows (P less than 0.001). In the larger herds it occurred more commonly where finishers were kept (P less than 0.05). Sow morbidity and management factors during the primary outbreak had no statistically significant effect on the incidence of recrudescence. Epidemiological aspects of the findings are discussed with emphasis on the difficulties associated with the diagnosis and control of endemic transmissible gastroenteritis infection.     

Effect of recombinant DNA-derived bovine alpha-1 interferon on transmissible gastroenteritis virus infection in swine

Recombinant DNA-derived bovine interferon alpha 1-1 (BoIFN) inhibited replication of both vesicular stomatitis virus and transmissible gastroenteritis virus in cultures of swine testicular cells. Newborn pigs were orally inoculated with BoIFN and subsequently had interferon in their gastric contents and serum; however, interferon was found only occasionally in intestinal washings. Incubation of BoIFN with gastric contents from a newborn suckling pig did not affect antiviral activity, whereas intestinal (small intestine) contents from the same animal inactivated BoIFN within 1 minute. Beginning at 6 hours of age, newborn, colostrum-deprived pigs were given 1 mg of BoIFN orally every 12 hours. These pigs were not protected against challenge exposure to virulent transmissible gastroenteritis virus at 48 hours of age; disease and mortality were similar for these pigs and for control pigs not given BoIFN prior to challenge exposure. The BoIFN did not impair growth rate of pigs and did not cause obvious disease or lesions.     

The effect of adoptive transfer of mononuclear leukocytes from an adult donor on spontaneous cell-mediated cytotoxicity and resistance to transmissible gastroenteritis in neonatal piglets.

The purpose of this study was to attempt to establish spontaneous cell-mediated cytotoxicity effector activity in the intraepithelial lymphocytes of neonatal piglets by adoptive transfer of mononuclear leukocytes from an adult donor and to determine the effect of transfer on the resistance of piglets to transmissible gastroenteritis. Cytotoxicity was determined by a chromium release assay using PK-15 cells persistently infected with transmissible gastroenteritis virus as targets. The experimental animals were inbred miniature pigs, in which a high degree of uniformity in lymphocyte defined histocompatibility complex antigens was demonstrated by the mixed lymphocyte reaction. Adoptive transfer of 8 X 10(7)-4 X 10(8) adult pig leukocytes established effector activity in eight recipient piglets, and leukocytes labelled with fluorescein isothiocyanate homed to the epithelium of the small intestine. When four recipients of 5 X 10(8) adult leukocytes were challenged with transmissible gastroenteritis virus, the onset of diarrhea was delayed for 24 h and the diarrhea was usually milder than in four untreated control piglets. It was concluded that the adoptive transfer of leukocytes with spontaneous cell-mediated cytotoxicity effector activity, which homed to the small intestinal epithelium, may have contributed to an increased resistance to transmissible gastroenteritis.     

猪两种腹泻病毒混合感染的病原诊断

对我省流行的疑似猪病毒性腹泻进行了病原诊断，通过细菌培养、ＲＮＡ电泳和电镜形态观察等辅助诊断和免疫萤光特异性诊断，确诊该病病原为猪传染性胃肠炎病毒（ＴＧＥＶ）与猪流行性腹泻病毒（ＰＥＤＶ）的混合感染，混合毒代号为ＴＰＶ３。