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为了整合前人的研究,进行综合判断,从循证医学角度对硒与GPx关系进行再认识.本研究通过检索多个数据库及相关资源,利用Meta分析的统计方法,将前人具有共同研究目的相互独立的多个研究结果合并、定量分析,剖析各研究间的差异特征.Meta分析结果表明,对照组与试验组之间鸡肝组织GPx活性差异显著(P<0.01),硒与GPx活性正相关.但Meta分析结果同时也指出,过去的研究中存在夸大或低估硒对GPx活性作用的事实,本研究中在日粮硒0.2 nag·kg~(-1)水平时,试验组鸡肝组织GPx活性比对照组提高26.79μg·mg~(-1)左右是具有统计学意义的.经典研究方法在鉴别硒与GPx关系方面所得出的结果总的倾向是可信的,但是具体到相关程度的研究则显得不够精确,甚至相互矛盾,这种历史现象也正反映了Meta分析的必要性,也与Meta分析在当今国际兽医学发展中的未来前景符合. 相似文献
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郑雪玥王祚万发春沈维军 《动物营养学报》2023,(10):6713-6725
于网状Meta分析方法,比较不同硒源对羊生长性能的影响,以期为羊生产中硒源的选择提供参考。计算机检索中国知网(CNKI)、万方(Wanfang)、PubMed和Web of Science数据库等,搜索有关硒源干预羊生长性能的所有试验研究,检索期限为各个数据库建库至2022年11月18日。采用STAIR清单对纳入的文献进行偏倚风险评价并汇总相关有效信息,使用ReVman 5.4.1软件、ADDIS v1.16.5软件和STATA 16.0软件进行贝叶斯模型网状Meta分析。结果表明:纳入39项研究,选定亚硒酸钠、酵母硒和硒代蛋氨酸进行网状Meta分析。与对照组相比,硒代蛋氨酸提高平均日采食量的概率最高(0.82),酵母硒提高平均日增重(0.59)和降低料重比(0.59)的概率最高。网状Meta分析表明,本研究选定的3种硒源在提高羊生长性能方面均具有良好的效果,以酵母硒效果最佳。 相似文献
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根据明确的检索策略和标准选取相关文献,收集整理各文献研究结果后利用Meta分析方法评价在日粮中添加茶多酚(Tea polyphenols,TP)对蛋鸡生产性能和蛋品质的影响,旨在为茶多酚在蛋鸡实际应用提供较为客观的综合性结论。结果显示:共有11篇文献纳入此次Meta分析;日粮中添加茶多酚显著提高蛋鸡产蛋率和平均蛋重,显著降低料蛋比;茶多酚还显著提高蛋黄颜色和减缓哈氏单位下降。综合得出在日粮中添加茶多酚对蛋鸡生产性能和蛋品质有一定的改善作用,200mg/kg添加水平具有较优的改善效果。 相似文献
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文章旨在利用Meta分析方法探究奶牛瘤胃pH和挥发性脂肪酸对奶牛生产性能的影响及其与瘤胃健康关系,并以此为例说明化学性屏障指标在评价畜禽消化道健康研究中的作用与可行性。Meta分析结果表明:瘤胃丁酸比例与乳糖含量具有显著的二次回归关系。与健康对照组相比,亚急性瘤胃酸中毒(SARA)奶牛瘤胃p H显著降低2.54个单位,总挥发性脂肪酸浓度、丙酸比例和丁酸比例显著增加,但乙酸比例显著降低,且发表间无偏倚性。Meta分析表明,瘤胃pH和挥发性脂肪酸可以作为评估牛瘤胃健康的指标,为畜禽消化道健康评定提供了数据支撑和方法参考。 相似文献
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《中国家禽》2020,(10)
为建立中药治疗鸭病毒性肝炎临床试验研究的系统评价,采用Meta分析方法,按照Cochrane手册指导纳入已发表的文献并以jadad量表进行评价,检索时间为从建库起至2020年1月,采用Stata 15.0软件以死亡率为效果指标进行Meta分析。结果显示:研究共纳入20篇文献,8 476例患鸭中分别包含治疗组4 133例及对照组4 343例,试验组均采用中药治疗,对照组分别采用西药治疗、抗体治疗和中药预防;随机效应模型表明中药治疗鸭病毒性肝炎的总死亡率显著低于西药治疗组(P0.01);固定效应模型分析显示,中药治疗组死亡率显著高于抗体治疗组(P0.05),极显著高于中药预防组(P0.01);发表偏倚分析结果表明,所采用的文献存在一定发表偏倚性。结果提示在雏鸭幼龄时可以服用中药预防鸭病毒性肝炎,发病时可采取抗体治疗或中药治疗降低死亡率。 相似文献
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文章旨在研究益生菌对肉鸡生长性能和肠道健康的影响。通过检索多个数据库及相关资源,从建库至2022年12月期间发表的相关的随机对照试验,利用Meta分析统计学的方法将相关研究结果进行合并分析处理。最终从2 922篇文献中筛选出14篇文献,共3 858只鸡纳入Meta分析。Meta分析的结果显示:在统计学上,饲料中添加益生菌可以显著降低肉鸡的料重比和日采食量,提高日增重(P<0.05);根据益生菌属进行亚组分析,不同类型益生菌对肉鸡料重比的影响效果不一致,饲料中添加乳酸菌的效果最佳。在肠道健康方面,饲料中添加益生菌显著提高鸡十二指肠[SMD=1.35,95%CI(0.13,2.58)(P<0.05)]和回肠[SMD=2.52,95%CI(1.29,3.74)(P<0.05)]的绒隐比,对空肠无显著影响[SMD=0.03,95%CI(-0.06,0.12)(P<0.05)]。敏感性分析结果均较为稳健,发表偏倚结果显示益生菌的添加对于日增重(P=0.012,P<0.05)和空肠的影响(P=0.035,P<0.05)存在发表偏倚,其余指标都不存在发表偏倚。文章... 相似文献
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目的:研究腹腔镜注射在病危猪治疗中的应用和效果.方法:选取30头病危猪作为研究样本,对该30头病危猪采取腹腔注射方式进行治疗,统计治疗结果,并进行分析.结果:共有29头病危猪被治愈,治愈率为96.67%.结论:腹腔注射方法对于病危猪有着较好的治疗效果,而且操作简单,不存在严重的不良反应,补液时间较短,可实现快速吸收,可以在病危猪的治疗当中进行推广. 相似文献
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Beran GW 《Preventive veterinary medicine》2008,86(3-4):198-207
When early people made their appearance, zoonotic infectious diseases were already waiting, but epidemic diseases did not appear in human history until people began to live in large numbers under conditions of close contact, mainly during the last 10,000 years. Disease has decimated urban populations, conquered armies, and disrupted society. The focus here is on (1) the plague of Athens and the Black Death; (2) smallpox, influenza, and rabies; (3) avian influenza prion diseases, and foot & mouth disease; and (4) emerging and re-emerging diseases. All have veterinary public health associations. In Athens, Greece, in 430 BC, when the Spartans ravaged the countryside, hordes crowded into Athens so that orderly movements, space in which to live, and adequate supplies of food became impossible. Crowding of any population fosters disease transmission; chaos and disorder enhance it all the more. Out of northern Egypt came a terrible plague from across the Mediterranean Sea. The identity of the plague of Athens remains unsure, but the well-considered conclusion is Rift Valley Fever, a mosquito borne, viral zoonosis. The Black Death, also called the Plague, raged in Asia for centuries. In 1347, the Black Death was brought by a ship out of Asia to Sicily. The scenes of devastation were repeated throughout Europe, with 90% or more of the people dying in city after city. Influenza, too, has been a cause of periodic human epidemics, but the great pandemic of influenza occurred in the last months of World War I. In the years of highest occurrence, more than half the world's population became clinically infected. If veterinary public health had been born earlier, it could have led to elucidating the epidemiology of influenza and the plagues of Athens, Europe, and Asia. In turn, smallpox had also caused continual tragedy. In 1796, Edward Jenner began to harvest pustules of cowpox from children or infected cows and inject them into susceptible children. In 1980, the World Health Organization declared that smallpox had been eliminated from the world. Rabies, though, still strikes terror. A number of animal diseases, broadly termed emerging and re-emerging diseases, need surveillance because they have the potential to impact human health. From late in 2003 to 2007, the highly pathogenic H5N1 influenza virus in poultry infected at least 121 people and caused 62 deaths in four countries. The prion diseases, too, all have very high numbers in concentrated contacts. To control these diseases, veterinary public health is essential, with diagnosis, epidemiological surveillance, clinical manifestations, and prevention as primary measures. 相似文献
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Dekker A Dercksen D Snoep J van Wuyjckhuise L 《Tijdschrift voor diergeneeskunde》2007,132(18):695-701
On 26th of july 2007 a new case of bluetongue was notified in the Netherlands and on 2nd of august 2007 foot-and-mouth disease was diagnosed in Surrey, England, which raised the threat of having both infections simultaniously in one area. Bluetongue and foot-and-mouth disease have a different pathogenesis, but symptoms may resemble each other at a later stage of infection. The pathogenesis and possible clinical symptoms of both infections are discussed and illustrated with pictures. 相似文献
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在动物的异常行为中以刻板行为最为常见,而咽气癖又是马最常见的口部刻板行为之一。作者就咽气癖在生理方面和心智方面对马体产生的影响、行为基础、诱因的研究进展及常见的防治措施进行综述。 相似文献
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近几年,世界饲用添加剂市场增长较快,预计今后将进一步增长,据世界粮农组织(FAO)首领会议的倡议,到2015年,将使世界营养不良的人口削减一半,其间,肉制品将会以每年2%的速度增长,特别是加快猪肉和禽肉增长。这将促进世界添加剂,尤其是蛋氨酸和赖氨酸需求量的增加。 相似文献
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