The major histocompatibility complex of West African cattle. Typing of lymphocyte antigens (BoLA) of Baoulé cattle (Bos taurus) and Sudanese zebus (Bos indicus) of Burkina Faso (West Africa)

Lymphocyte antigen (BoLA) typing on 247 Baoule cattle (Bos taurus) and 106 Sudanese zebus (Bos indicus), allowed us to determine gene frequencies of 43 class 1 specificities, as international "W" and European "EU", as African local from Kenya "KN" and Burkina Faso "BF". In comparing these frequencies, it appears that some specificities could be considered as significant breed markers for Baoule cattle and zebus.     

Effects of anticoagulants and storage (4°C) on packed cell volume (PCV) of Nigerian domestic fowl (Gallus domesticus) and guinea fowl (Numida meleagris)

1. Studies were conducted to determine the effects of anticoagulants and storage (4°C) on the PCV of blood samples from Nigerian domestic fowl (DF) and the guinea fowl (GF).

2. Citrate significantly reduced pre‐storage PCV of the DF in comparison with the effect of ethylenediamine tetra‐acetic acid (EDTA).

3. It further decreased (P<0.05) the PCV of the blood of DF and GF over 3 d of storage; this was similar to the effect of EDTA on the PCV of the GF blood.

4. Citrate and oxalates induced haemolysis of blood of the DF and the GF in storage faster than EDTA, but overall the haemolysis was more pronounced from red cells of the GF than from those of the DF.

5. The mean fall in the PCV of the DF was significant at 3.0 mg EDTA/ml of blood in contrast to the fall in the PCV of the GF blood.     

A Survey of the Literature (1995–1999) on the Kinetics of Drugs in Camels (Camelus dromedarius)

Recent publications dealing mainly with the kinetics of antiparasitic and antibacterial agents, NSAIDs, and other drugs in camels are briefly reviewed. The kinetic data for most of these drugs indicated that they have longer absorption and elimination half-lives and slower systemic clearance in the camel compared to other animals. This corroborates earlier reports that suggested that the activities of drug-metabolizing enzymes and the capacity to biotransform and eliminate xenobiotics is lower in camels than in other ruminants. There is a clear need to establish basic kinetic data for the camel in order to avoid extrapolation of drug dosage regimens and withdrawal times from data for other animals, as this may result in irrational use of drugs in camels.     

Recovery of Fascioloides magna (Digenea) population in spite of treatment programme? Screening of Galba truncatula (Gastropoda, Lymnaeidae) from Lower Austria

During the past decade, Fascioloides magna, the large American liver fluke, has spread within free-living deer in wetlands of the Danube in Lower Austria. The aim of this study was to determine the current infection rates with F. magna and other digenean parasites in the intermediate host snail Galba truncatula from risk areas in Lower Austria. A total of 3444 G. truncatula were collected and examined microscopically for the presence of digenean trematodes. A set of randomly selected snails and isolated trematode stages were also investigated molecular biologically by PCR and sequencing. Digenean parasites were detected with a prevalence of 2.41% (1.83% Paramphistomoidea; 0.46% Echinostomatoidea; 0.09% Strigeida; 0.06% Plagiorchiida). F. magna was found with an overall prevalence of 0.23%, which may indicate a recovery of the parasite population in spite of an ongoing triclabendazole treatment programme. Moreover, high risk areas and a seasonality of infections were observed.     

Chiral Inversion of (R)-(–)-Fenoprofen in Guinea-pigs Pretreated with Clofibrate

The influence of clofibrate on the stereoconversion of fenoprofen (FPF) was studied in guinea pigs. This hypolipidaemic agent has been related to some biochemical changes in the liver leading to an increase in the chiral inversion process. Two groups of animals (n = 6 per group) were pretreated with oral doses of clofibrate (280 mg/kg per day) for three days and were then given (R)- or (S)-FPF (5 mg/kg, IV). The FPF enantiomers were extracted from the guinea-pigs' plasma using a solid phase procedure and analysed by HPLC with previous derivatization with L-leucinamide. Pretreatment with clofibrate increased the chiral inversion of (R)-FPF in favour of the pharmacologically active (S)-FPF enantiomer. Before this metabolic interaction can be applied to therapy with fenoprofen, the toxic effects of (S)-(+)-FPF on the gastrointestinal and renal tracts and the interference by (R)-(–)-FPF with the metabolism of lipids should be thoroughly evaluated.     

Effect of replacing soybean protein by taro leaf (Colocasia esculenta (L.) Schott) protein on growth performance of exotic (Landrace × Yorkshire) and native (Moo Lath) Lao pigs

The impact of replacing soybean crude protein (CP) with CP from ensiled taro leaves (ET) on growth performance, carcass traits, and organ weights in Landrace × Yorkshire (LY) and Moo Lath (ML) Lao pigs was studied. Twenty-four castrated male pigs, 12 of each breed, were allocated to the treatments according to a completely randomized 3?×?2 factorial (three levels of ET × two breeds) arrangement with four pigs per treatment. The pigs were kept in individual pens and were fed at 4 % dry matter of body weight for 105 days. The control diet (ET0) was formulated with soybean meal as the main CP source, and in the other two diets, soybean CP was replaced to 25 % (ET25) and 50 % (ET50), respectively, with CP from ensiled taro leaves. Calculated metabolizable energy intake decreased with increasing replacement of soybean CP in the diet, while dry matter intake (DMI), CP intake (CPI), average daily gain (ADG), and feed conversion ratio (FCR) were unaffected. Carcass weight, back fat thickness, and dressing percentage were unaffected by soybean CP replacement, while organ weights (except for spleen) increased (P?<?0.001) when soybean CP was replaced by CP from ensiled taro leaves in the diet. LY pigs had higher (P?<?0.001) DMI, CPI, and ADG and better (P?<?0.001) FCR than ML pigs. LY pigs had higher carcass weight (P?<?0.001), lower back fat thickness (P?<?0.001), and higher organ weights (P?<?0.05–0.001) than the ML pigs. In conclusion, taro leaf silage can replace up to 50 % of soybean CP in the diet of growing Lao LY and ML pigs without negative effects on performance and carcass traits.     

Pharmacokinetic Parameters of (R)-(−) and (S)-(+)-Flurbiprofen in Dairy Bovines

The aim of the study was to evaluate the pharmacokinetics of flurbiprofen (FBP) in different age groups and physiological status groups in dairy cattle. Ten Argentine Holstein bovines were divided into three different groups: 3 cows in early lactation, 3 cows in gestation and 4 newborn calves. Based on previous experience, all the animals received racemic FBP (50:50) at a dose of 0.5 mg/kg by intravenous administration. Blood samples were taken at predetermined times after administration of flurbiprofen. Plasma enantiomer concentrations were measured by HPLC. Total body clearance (ClB) of (S)-(+)-FBP was higher in calves than in cows (114.5, 136.4, 121.4, 128.9 μg/ml vs 22.0, 24.2, 46.5 μg/ml and 27.6, 25.3, 34.6 μg/ml). In calves the disposition kinetics showed stereoselective behaviour. Area under the concentration–time curve (AUC) was higher and Cl_B and steady-state volume of distribution (V_ss) were lower for (R)-(−)-FBP than for (S)-(+)-FBP. In cows, stereoselectivity was observed in Cl_B and elimination half-life (fract₁2)(frac{t_1}{2}) only in the early lactation group. In this study, enantioselective metabolic behaviour of FBP under the physiological situations studied was found. Hence, it is possible that both enantiomers of flurbiprofen may contribute to the drug's therapeutic effects, but further studies with the administration of separate enantiomers will be required to elucidate their metabolism.     

Treatment of fibroepithelial hyperplasia (FEH) of the mammary gland in the cat with the progesterone antagonist Aglépristone (Alizine)

Three cases of fibroepithelial hyperplasia (FEH) of the mammary gland in the cat are reported. A one year old female cat had a distinct enlargement of the middle mammary glands, one on each side, 5 days after the first estrus. One week later the cat was treated with medroxyprogesterone acetate (Depo-Promone). The affected glands, along with the remaining glands, increased further in size. A five year old female cat was treated with Proligeston (Covinan) for the suppression of estrus. Two weeks later fibroepithelial hyperplasia occurred in two glands, one with a well demarcated ulceration. A seven months old male cat was treated with delmadinon acetate (Tarden) because of urine spraying. Two months later he had enlargement of all mammary glands. All three cats were treated with the progesterone antagonist Aglépristone (Alizine). Within 5 to 11 weeks the mammary glands had regressed to normal.     

Swellings of the angle of the mandible in 32 horses (1997–2011)

Disorders of the horizontal ramus (body) of the equine mandible are well reported, but there is minimal documentation of disorders of the angle of mandible. A retrospective examination of the records of Edinburgh University Equine Hospital (1997–2011) showed that 32 horses were referred due to swellings of the angle of the mandible. The aetiology of these swellings was identified in just 13/32 cases (41%) including fractures (n = 2), traumatic, localised periosteal/cortical lesions (n = 4), traumatic soft tissue lesions (n = 2), neoplasia (n = 3), and inflammation of the adjacent salivary gland (n = 1) and masseter muscle (n = 1).The remaining 19 (59%) cases without a definitive diagnosis showed two patterns of lesions. Twelve cases had localised periosteal/cortical lesions of the ventral aspect of the angle of mandible that were most likely traumatic in origin. The remaining seven undiagnosed cases without mandibular bony changes all had sinus tracts/chronic soft tissue infections on the medial aspect of the angle of the mandible which were believed to be caused by a draining retro-pharyngeal lesion in five cases. Surgical excision of abnormal soft tissues (if present) and bone curettage was the most successful treatment.It was concluded that the aetiology of swellings of the angle of the equine mandible are often obscure; most appear to be traumatic in origin, yet horses seldom develop gross fractures at this site due to the support of the dense surrounding musculo-tendinous structures. A smaller proportion are caused by draining retropharyngeal lesions that respond poorly to medical therapy, but respond well to surgical treatment.     

欢迎订阅2018年Journal of Integrative Agriculture(JIA)

正《农业科学学报》(Journal of Integrative Agriculture,JIA)由农业部主管、中国农业科学院与中国农学会共同主办,是综合性英文学术期刊,月刊。JIA前身为2002年创刊的《中国农业科学》英文版(Agricultural Sciences in China,ASC),2012年更名为JIA。JIA 2006年起与Elsevier合作,全文数据在ScienceDirect平台面向世界发行;2009年被SCI收录,最新影响因子为1.042,位于     

欢迎订阅2018年Journal of Integrative Agriculture(JIA)

<正>《农业科学学报》(Journal of Integrative Agriculture,JIA)由农业部主管、中国农业科学院与中国农学会共同主办,是综合性英文学术期刊,月刊。JIA前身为2002年创刊的《中国农业科学》英文版(Agricultural Sciences in China,ASC),2012年更名为JIA。JIA 2006年起与Elsevier合作,全文数据在ScienceDirect平台面向世界发行;2009年被SCI收录,最新影响因子为1.042,位于JCR     

欢迎订阅2020年Journal of Integrative Agriculture(JIA)

正《农业科学学报》(Journal of Integrative Agriculture,JIA)由农业农村部主管、中国农业科学院与中国农学会共同主办,是综合性英文学术期刊,月刊。JIA前身为2002年创刊的《中国农业科学》英文版(Agricultural Sciences in China,ASC),2012年更名为JIA。JIA 2006年起与Elsevier合作,全文数据在ScienceDirect平台面向世界发行;2009年被SCI收录,最新影响因子为1.337,位于JCR农业综合类Q2区前列位     

Prepuberal evolution of plasma leptin levels in gilts of thrifty genotype (Iberian pig) and lean commercial crosses (Large White × Landrace)

Current study aimed to determine possible differences in plasma leptin levels during the prepuberal period and their relationship with the onset of puberty in gilts of obese thrifty genotype (Iberian breed) and lean genotype (Large White × Landrace commercial crosses) reared under similar conditions. Plasma leptin concentration increased linearly during the 7 weeks prior to the day of puberty attainment in both genotypes (P<0.005, r=0.707 for LW × L and P<0.0005, r=0.874 for Iberian gilts). However, leptin levels in the Iberian gilts was higher from the first sample of the experimental period, with females having 16 weeks-old (2.7±0.3 vs 1.7±0.2 ng/ml in LW × L; P<0.001), to the onset of puberty (8.5±0.7 vs 2.8±0.3 ng/ml in LW × L; P<0.005). Thus, the current study reinforces previous data on changes in around puberty and evidences, for the first time, profound differences in prepuberal plasma leptin levels between gilts of obese (Iberian) and lean genotypes (LW×L).     

欢迎订阅2019年Journal of Integrative Agriculture(JIA)

正《农业科学学报》(Journal of Integrative Agriculture,JIA)由农业部主管、中国农业科学院与中国农学会共同主办,是综合性英文学术期刊,月刊。JIA前身为2002年创刊的《中国农业科学》英文版:(:Agricultural Sciences in China,ASC),2012年更名为JIA。JIA 2006年起与Elsevier合作,全文数据在ScienceD irect平台面向世界发行;2009年被SCI收录,最新影响因子为1.042,位于JCR农业综合类     

Use of pimobendan in 170 cats (2006–2010)

Hypothesis/ObjectivesTo describe the therapeutic use of pimobendan in cats, describe the patient population to which it was administered, document potential side effects and report the clinical course following administration of pimobendan in conjunction with standard heart failure therapy. It is hypothesized that cats with advanced heart disease including congestive heart failure from a variety of causes will tolerate pimobendan with a minimum of side effects when used in treatment in conjunction with a variety of other medications.Animals, materials and methodsOne hundred and seventy client owned cats with naturally occurring heart disease, one hundred and sixty four of which had congestive heart failure. Medical records were reviewed and owners and referring veterinarians were contacted for follow-up data. Data collected included pimobendan dose, other medications administered concurrently, data collected at physical examination, presence or absence of heart failure, adverse effects, classification of heart disease, echocardiographic data and survival time. The data were analyzed for significance between the initial visit and any follow-up visits.ResultsAll cats were treated with pimobendan. The median pimobendan dose was 0.24 mg/kg q 12 h. Pimobendan was used in combination with multiple concurrent medications including angiotensin converting enzyme inhibitors, diuretics and anti-thrombotics. Five cats (3.0%) had potential side effects associated with pimobendan. One cat (0.6%) had presumed side effects severe enough to discontinue pimobendan use. Median survival time for 164 cats with congestive heart failure after initiation of pimobendan was 151 days (range 1–870).ConclusionPimobendan appears to be well tolerated in cats with advanced heart disease when used with a variety of concurrent medications. Randomized controlled studies need to be performed to accurately assess whether it is efficacious for treatment of congestive heart failure in cats.     

欢迎订阅2019年Journal of Integrative Agriculture(JIA)

正《农业科学学报》(Journal of Integrative Agriculture,JIA)由农业部主管、中国农业科学院与中国农学会共同主办,是综合性英文学术期刊,月刊。JIA前身为2002年创刊的《中国农业科学》英文版(Agricultural Sciences in China,ASC),2012年更名为JIA。JIA 2006年起与Elsevier合作,全文数据在ScienceDirect平台面向世界发行;2009年被SCI收录,最新影响因子为1.042,位于JCR农业综合类Q2区前列位次。JIA是中国科技核心期     

欢迎订阅2018年Journal of Integrative Agriculture (JIA)

<正>《农业科学学报》(Journal of Integrative Agriculture,JIA)由农业部主管、中国农业科学院与中国农学会共同主办,是综合性英文学术期刊,月刊。JIA前身为2002年创刊的《中国农业科学》英文版(Agricultural Sciences in China,ASC),2012年更名为JIA。JIA 2006年起与Elsevier合作,全文数据在ScienceDirect平台面向世界发行;2009年被SCI收录,最新影响因子为1.042,位于JCR农业综合类Q2区前列位次。JIA     

欢迎订阅2020年Journal of Integrative Agriculture(JIA)

正《农业科学学报》(Journal of Integrative Agriculture,JIA)由农业农村部主管、中国农业科学院与中国农学会共同主办,是综合性英文学术期刊,月刊。JIA前身为2002年创刊的《中国农业科学》英文版(Agricultural Sciences in China,ASC),2012年更名为JIA。JIA 2006年起与Elsevier合作,全文数据在Science Direct平台面向世界发行;2009年被SCI收录,最新影响因子为1.337,位于JCR农业综合     

Evaluation of butorphanol–azaperone–medetomidine (BAM) in captive blesbok immobilization (Damaliscus pygargus phillipsi)

Objective

The fixed-dose combination of butorphanol, azaperone and medetomidine (BAM; 30, 12 and 12 mg mL^?1, respectively) with subsequent antagonism by naltrexone–atipamezole was evaluated for reversible immobilization of captive blesbok (Damaliscus pygargus phillipsi).

Evaluation of BAM (butorphanol–azaperone–medetomidine) in captive African lion (Panthera leo) immobilization

Objective

The combination of butorphanol, azaperone and medetomidine (BAM) with subsequent antagonism by naltrexone–yohimbine or naltrexone–atipamezole was evaluated for reversible immobilization of captive African lions (Panthea leo).