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蓝舌病病原分子生物学及免疫学研究进展
引用本文:王荣亮,胡骑,信爱国.蓝舌病病原分子生物学及免疫学研究进展[J].中国畜牧兽医,2011,38(8):177-181.
作者姓名:王荣亮  胡骑  信爱国
作者单位:1. 云南农业大学动物科技学院,云南昆明 650201;云南省畜牧兽医科学院云南省热带亚热带动物病毒重点实验室,云南昆明650224
2. 云南省畜牧兽医科学院云南省热带亚热带动物病毒重点实验室,云南昆明,650224
摘    要:蓝舌病病毒通过吸血昆虫(库蠓)在易感反刍动物之间叮咬进行传播。在家畜中,蓝舌病易发于某些品种的羊,具有典型症状,呈地方性流行;牛感染蓝舌病通常不表现出临床症状。作者分析和总结了近年蓝舌病疫情发生和传播可能的潜在路线,病毒分子生物学研究概况,致病机理及宿主对蓝舌病病毒的免疫反应,并对蓝舌病疫苗的研究进展作了介绍,建议要加强对该病的深入研究,防患于未然。

关 键 词:蓝舌病病毒  流行情况  病原分子生物学  免疫学  
收稿时间:2010-12-15

Progress on Pathogen Molecular Biology and Immunology of Bluetongue
WANG Rong-liang,HU Qi,XIN Ai-guo.Progress on Pathogen Molecular Biology and Immunology of Bluetongue[J].China Animal Husbandry & Veterinary Medicine,2011,38(8):177-181.
Authors:WANG Rong-liang  HU Qi  XIN Ai-guo
Affiliation:1. College of Aninal Science and Technology,Yunnan Agricultural University,Kunming 650201,China;2. Yunnan Tropical and Subtropical Animal Virus Disease Laboratory,Yunnan Animal Science and Veterinary Institute,Kunming 650224,China
Abstract:Bluetongue virus (BTV) is transmitted from infected to susceptible ruminants by hematophagous vector midges (Culicoides species).Amongst domestic livestock,bluetongue is most common in certain breeds of sheep. BTV infection of sheep with clinical symptom is typical in enzootic regions. BTV infection of cattle are most common,whereas asymptomatic. This review analysed and summarized the BTV epidemic situation and potential spread of disease transimission line,as well as the progress on the molecular biology and pathogensis of BTV and the host immune response against BTV. Furthermore,the advances on vaccine of BTV were descirbed,and also suggested to enhance the study of BTV for provention BTV in the future.
Keywords:bluetongue virus(BTV)  epidemic situation  pathogen molecular biology  immunology
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