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促黄体素释放激素和多巴胺拮抗物对鲇促性腺激素释放的作用
引用本文:温海深.促黄体素释放激素和多巴胺拮抗物对鲇促性腺激素释放的作用[J].水产学报,2001,25(5):393-397.
作者姓名:温海深
作者单位:中山大学生命科学学院,
基金项目:国家自然科学基金资助项目(39970586)
摘    要:以珠江流域鲇为研究对象,分别在性腺发育早期、性腺发育晚期、性腺发育成熟与产卵前期、性腺退化期注射促黄体素释放激素类似物和多巴胺D2受体拮抗物,处理后6h、12h、24h测定血液中的促性腺激素水平变化。结果表明,在性腺发育的各个时期,促黄体素释放激素类似物和多巴胺D2受体拮抗物联合注射能显著剂激鲇促性腺激素分泌;鲇脑垂体促性腺激素的分泌受下丘脑释放的促性腺素释放激素和多巴胺的双重调节,多巴胺只能抑制促性腺素释放激素诱导的促性腺激素分泌。在建立鲇人工繁殖技术时,可采用促黄体素释放激素类似物和多巴胺D2受体拮抗物联合注射方法。

关 键 词:  促性腺激素  促黄体素释放激素  多巴胺受体拮抗物
文章编号:1000-0615(2001)05-0393-05
收稿时间:2014/4/14 0:00:00
修稿时间:2000年4月21日

Effect of LHRH-A and domperidone on gonadotropin releasing in Silurus asotus
WEN Hai-shen.Effect of LHRH-A and domperidone on gonadotropin releasing in Silurus asotus[J].Journal of Fisheries of China,2001,25(5):393-397.
Authors:WEN Hai-shen
Affiliation:School of Life Science, Zhongshan University, Guangzhou 510275, China
Abstract:To catfish( Silurus asotus) of Pearl Rever, in the stage of early gonadal development, the stage of late gonadal development, mature and preovulatory stage, and the sexually regressed stage, luteinizing hormone-releasing hormone analogue (LHRH-A) and dopamine antagonist, domperidone(DOM) were injected, and then GtH levels of serum were sampled and assayed using the radioimmunoassay after 6h, 12h and 24h. The results indicated that it could enhance significantly GtH levels of serum by injection of LHRH-A plus DOM in every gonadal periods; GtH secretion in catfish was under a dual control of gonadotropin-releasing hormone (GuRH) and dopamine ( DA) released from the hypothalamus, and DA could only inhibit 0tH induced by GnRH from releasing; the combination of LHRH-A and DOM could be used to induce ovulation in catfish.
Keywords:Silurus asotus  gonadotropin  luteinizing hormone-releasing hormone analogue  dopamine antagonist
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