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苯并_a_芘对大弹涂鱼肝脏芳烃羟化酶活性的影响
引用本文:冯涛.苯并_a_芘对大弹涂鱼肝脏芳烃羟化酶活性的影响[J].水产学报,2001,25(2):156-160.
作者姓名:冯涛
作者单位:1. 厦门大学环境科学研究中心,
2. 厦门大学海洋系,
基金项目:国家自然科学基金资助项目(49876029)
摘    要:研究了苯并(a)芘(BaP)胁迫下大弹涂鱼肝脏芳烃羟化酶(AHH)活性的变化,结果显示BaP对大弹涂鱼肝脏AHH活性总体表现为显著的诱导作用(P<0.01),其中BaP暴露的浓度及时间是影响AHH活性的重要因素.0.05mg@L-1浓度的BaP暴露对AHH活性无显著影响,而0.2mg@L-1和0.5mg@L-1浓度组AHH活性则显著被诱导(P<0.01).随着暴污时间的延长,0.2mg@L-1浓度组AHH活性被显著诱导(P<0.01),而0.5mg@L-1组AHH活性则相对稳定.对AHH活性变化的剂量-效应关系进行回归分析的结果表明,0.5mg@L-1浓度组暴露7d时,AHH活性受到一定程度的抑制.污染解除后,0.5mg@L-1浓度组AHH活性显著降低,恢复至与对照组相近,表明大弹涂鱼肝脏仍具有较强的生理调节机能,同时也表明AHH活性可及时反映环境中BaP的水平.以上这些结果表明AHH适于作为大弹涂鱼受BaP胁迫的生物指标.

关 键 词:苯并(a)芘  大弹涂鱼  芳烃羟化酶  肝脏  海洋污染  生物指标
文章编号:1000-0615(2001)02-0156-05
收稿时间:2014/4/15 0:00:00
修稿时间:2000年8月14日

Effects of benzo(a)pyrene exposure on aryl hydrocarbon hydroxylaseactivities in the liver of Boleophthalmus pectinirostris
FENG Tao.Effects of benzo(a)pyrene exposure on aryl hydrocarbon hydroxylaseactivities in the liver of Boleophthalmus pectinirostris[J].Journal of Fisheries of China,2001,25(2):156-160.
Authors:FENG Tao
Affiliation:FENG Tao 1,ZHENG Wei yun 1,HONG Wan shu 2,ZHANG Qi yong 2
Abstract:Changes of aryl hydrocarbon hydroxylase(AHH) activities in the liver of Boleophthalmus pectinirostris with benzo(a)pyrene(BaP) exposure were detected in experimental condition. The results showed that the activities of AHH were significantly induced by BaP(P<0.01). Factors including BaP concentration and exposure time had important effect on AHH activities. The activities of AHH decreased to the control level after BaP was removed. It turned out that the physiological modulatary mechanism was still exist in the liver of B. pectinirostris and the activities of AHH could reflect the level of BaP in the environment. All of the results showed that AHH was suitable to be the bioindicator of BaP exposure.
Keywords:Benzo(a)pyrene (BaP)  Boleophthalmus pectinirostris  aryl hydrocarbon hydroxylase(AHH)
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