| 虎潜丸加减方治疗肾阴虚型原发性骨质疏松症骨性疼痛的疗效观察 |
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| 作者姓名： | 罗江 |
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| 作者单位： | 清华大学玉泉医院干部医疗科, 北京 100040 |
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| 摘 要： | 目的 观察虎潜丸加减方对肾阴虚型原发性骨质疏松症的止痛效果。方法 将肾阴虚型原发性骨质疏松症患者136例，采用随机数字表法分为对照组66例和观察组70例。对照组予常规西医治疗，观察组在对照组基础上给予虎潜丸加减方，2组疗程均为3个月。用视觉模拟评分法与MgGee疼痛标尺法评估两组患者治疗前后的疼痛评分，并比较两组患者骨质疏松症症状评分、骨密度变化及不良反应发生情况。结果 观察组治疗后视觉模拟评分法与MgGee疼痛标尺法的评分均显著低于对照组（P<0.05），骨质疏松症各项临床症状评分均较对照组下降明显（P<0.05）；治疗后两组患者骨密度测值均无明显变化（P>0.05），且两组患者均未出现严重药物不良反应。结论 虎潜丸加减方可改善肾阴虚型原发性骨质疏松症患者各项临床症状，抑制骨性疼痛，且可维持患者骨量，无明显不良反应，值得临床推广。
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| 关 键 词： | 原发性骨质疏松症 骨性疼痛 虎潜丸加减方 肾阴虚 临床疗效 |
| 收稿时间： | 2018/3/1 0:00:00 |
Clinical Efficacy Observation on Modified Huqian Pills in the Treatment of Bone Pain of Primary Osteoporosis with Kidney Yin Deficiency Syndrome |
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| Authors: | LUO Jiang |
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| Affiliation: | Department of Special Medical Treatment, Tsinghua University Yuquan Hospital, Beijing 100040, China |
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| Abstract: | Objective To explore the analgesic effects of modified Huqian Pills on primary osteoporosis with kidney Yin deficiency syndrome. Methods A total of 136 cases of patients with primary osteoporosis of kidney Yin deficiency syndrome were divided into the control group of 66 cases, and the observation group of 70 cases according to the random number table. The control group was given conventional Western medicine treatment, and the observation group was added modified Huqian Pills. Both groups were treated for 3 months. The visual analogue pain scores and MgGee pain scale were used to evaluate the pain scores of 2 groups before and after treatment. The osteoporosis symptom score, the changes in bone mineral density and the adverse reaction of 2 groups were compared. Results After treatment, the visual analogue pain scores and the MgGee pain scale of the observation group were significantly lower than the control group (P<0.05). The clinical symptom scores of osteoporosis were decreased significantly than the control group (P<0.05). There were no significant changes in bone mineral density measurements of 2 groups after treatment (P>0.05). There were no serious adverse drug reactions in 2 groups. Conclusion Modified Huqian Pills can improve the clinical symptoms of primary osteoporosis patients with kidney Yin deficiency syndrome, inhibit bone pain, and can maintain bone mass, without obvious adverse drug reaction, which is worthy of clinical promotion. |
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| Keywords: | primary osteoporosis bone pain modified Huqian Pills kidney Yin deficiency clinical efficacy |
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