| 全基因组SNP分型技术在畜禽遗传育种研究中的应用 |
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| 引用本文： | 刘继强,郝晓东,武丽娜,廖诗莹,冯羿方,弥世荣,刘燊,刘建,张龙超. 全基因组SNP分型技术在畜禽遗传育种研究中的应用[J]. 畜牧兽医学报, 2022, 53(12): 4123-4137. DOI: 10.11843/j.issn.0366-6964.2022.12.001 |
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| 作者姓名： | 刘继强 郝晓东 武丽娜 廖诗莹 冯羿方 弥世荣 刘燊 刘建 张龙超 |
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| 作者单位： | 1. 北京康普森农业科技有限公司, 北京 102200;2. 江西正邦养殖有限公司, 南昌 330096;3. 中国农业科学院北京畜牧兽医研究所, 北京 100193 |
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| 基金项目： | 江西省重大科技研发专项 (20194ABC28008) |
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| 摘 要： | 随着畜禽资源分子鉴定、物种进化、全基因组育种等热点领域的逐渐兴起，准确的全基因组SNP分型成为了畜禽基因组研究的关键。基因芯片、重测序、简化基因组测序及靶向捕获测序等全基因组SNP分型技术已广泛应用于畜禽基因组研究中。本文概述了全基因组SNP分型技术的原理及其在全基因组关联分析、选择信号分析和畜禽遗传资源背景分析等方面的应用，以期为畜禽基因组研究和育种应用提供借鉴和参考。
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| 关 键 词： | 基因分型 基因组研究 基因芯片 二代测序 |
| 收稿时间： | 2022-05-06 |
Application of Whole Genome SNP Genotyping Technology in Livestock and Poultry Genetics and Breeding |
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| LIU Jiqiang,HAO Xiaodong,WU Lina,LIAO Shiying,FENG Yifang,MI Shirong,LIU Shen,LIU Jian,ZHANG Longchao. Application of Whole Genome SNP Genotyping Technology in Livestock and Poultry Genetics and Breeding[J]. Chinese Journal of Animal and Veterinary Sciences, 2022, 53(12): 4123-4137. DOI: 10.11843/j.issn.0366-6964.2022.12.001 |
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| Authors: | LIU Jiqiang HAO Xiaodong WU Lina LIAO Shiying FENG Yifang MI Shirong LIU Shen LIU Jian ZHANG Longchao |
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| Affiliation: | 1. Beijing Compass Agritechnology Co. Ltd., Beijing 102200, China;2. Jiangxi Zhengbang Breeding Co. Ltd., Nanchang 330096, China;3. Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China |
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| Abstract: | With the universal use of molecular identification, species evolution analysis and whole-genome breeding, accurate genomic-wide SNP genotyping has become the key to genome research in livestock and poultry. Genotyping array, whole genome resequencing (WGS), reduced-representation genome sequencing (RRGS) and target capture sequencing have been widely used in livestock and poultry genomic research. In this paper, the principle of genomic-wide SNP genotyping technology and its application in genome-wide association studies, selection signal analysis and background analysis of livestock and poultry genetic resources were summarized, in order to provide reference for livestock and poultry genome research and genetic breeding. |
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| Keywords: | genotyping genome research gene chip next-generation sequencing |
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