Effects of the butyric acid‐producing strain Clostridium butyricum MIYAIRI 588 on broiler and piglet zootechnical performance and prevention of necrotic enteritis |
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| Authors: | Motomichi Takahashi Elinor McCartney Anne Knox Maria Francesch Kentaro Oka Kaoruko Wada Marie Ideno Koji Uno Krzysztof Koz?owski Jan Jankowski Marta I Gracia Joaquin Morales Spyridon K Kritas Enric Esteve‐Garcia Shigeru Kamiya |
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| Affiliation: | 1. Tokyo R&D Centre, Miyarisan Pharmaceutical Co., Ltd., Kita‐ku, Tokyo, Japan;2. Department of Infectious Diseases, Kyorin University School of Medicine, Mitaka, Tokyo, Japan;3. Pen & Tec Consulting S.L.U., Sant Cugat del Vallès, Barcelona, Spain;4. Roslin Nutrition Ltd., East Lothian, Scotland;5. Animal Nutrition, IRTA Centre Mas Bover, Constanti, Spain;6. Department of Poultry Science, Faculty of Animal Bioengineering, Olsztyn University of Warmia and Mazury, Olsztyn, Poland;7. Imasde Agroalimentaria S.L., Pozuelo de Alarcon, Madrid, Spain;8. PigCHAMP Pro Europa S.L., Segovia, Spain;9. Department of Microbiology and Infectious Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Macedonia, Greece |
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| Abstract: | The objective of this study was to assess the effects of a probiotic strain Clostridium butyricumMIYAIRI 588 (CBM588) on broiler and weaned piglet health and zootechnical performance. Five field studies were carried out in broilers and five in weaned piglets under European feed additive guidelines. Each study followed a randomized blocked design with two treatments: Control (basal diet) and CBM588 supplemented groups. The zootechnical performance parameters selected were body weight, daily gain, feed intake and feed efficiency (feed:gain). Broilers fed diets with CBM588 gained significantly more weight (+2%, p < .001) and exhibited significantly better feed efficiency (?1.6%, p < .001) in comparison with Controls. Similarly, analysis of pooled data of weaned piglet trials showed that CBM588‐fed piglets were significantly heavier than Controls (+2.6%, p = .014), exhibited significantly higher mean daily gain (+4.7%; p = .004), and significantly improved feed efficiency (?4.2%, p = .001). In addition to the zootechnical efficacy studies, the preventive effect of CBM588 on necrotic enteritis (NE) was assessed in a natural challenge model in broilers where CBM588 reduced the incidence and severity of NE lesions. These data indicate the potential of CBM588 to improve broiler and weaned piglet zootechnical performance, and to make a positive contribution to animal health. |
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| Keywords: | Clostridium butyricumMIYAIRI 588 necrotic enteritis probiotics zootechnical performance |
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