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Recommendations for designing and conducting veterinary clinical pathology biologic variation studies
Authors:Kathleen P Freeman  Randolph M Baral  Navneet K Dhand  Søren Saxmose Nielsen  Asger L Jensen
Affiliation:1. IDEXX Laboratories, Ltd., Wetherby, West Yorkshire, UK;2. Paddington Cat Hospital, Paddington, NSW, Australia;3. Faculty of Veterinary Science, The University of Sydney, Sydney, NSW, Australia;4. Department of Large Animal Sciences, University of Copenhagen, Frederiksberg C, Denmark;5. Department of Veterinary Clinical and Animal Sciences, University of Copenhagen, Frederiksberg C, Denmark
Abstract:The recent creation of a veterinary clinical pathology biologic variation website has highlighted the need to provide recommendations for future studies of biologic variation in animals in order to help standardize and improve the quality of published information and to facilitate review and selection of publications as standard references. The following recommendations are provided in the format and order commonly found in veterinary publications. A checklist is provided to aid in planning, implementing, and evaluating veterinary studies on biologic variation (Appendix  S1 ). These recommendations provide a valuable resource for clinicians, laboratorians, and researchers interested in conducting studies of biologic variation and in determining the quality of studies of biologic variation in veterinary laboratory testing.
Keywords:Laboratory testing  quality specifications  reference change value
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