Computed Tomographic Angiography of the Pancreas in Cats with Chronic Diabetes Mellitus Compared to Normal Cats |
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Authors: | S Secrest A Sharma A Bugbee |
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Affiliation: | 1. Department of Veterinary Biosciences and Diagnostic Imaging, University of Georgia College of Veterinary Medicine, Athens, GA;2. Department of Small Animal Medicine and Surgery, University of Georgia College of Veterinary Medicine, Athens, GA |
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Abstract: | Background Diabetes mellitus (DM) is a common endocrinopathy in cats. No known diagnostic test or patient characteristic at the time of diagnosis can predict likely disease course, unlike in people in whom computed tomographic angiography (CTA) is used. No published data exist regarding the CTA appearance of the pancreas in cats with DM, and thus, it is unknown what if any CTA variables should be further assessed for associations with pancreatic endocrine function. Hypothesis/Objectives A significant difference in pancreatic attenuation, volume, and size will be identified between normal cats and those with chronic DM on CTA. Animals Ten healthy control cats and 15 cats with naturally occurring DM present for >12 months. Methods Prospective cross‐sectional study comparing pancreatic attenuation, enhancement pattern, size, volume, pancreatic volume‐to‐body weight ratio (V:BW), pancreatic arterial: portal phase ratio (A:P), time‐to‐arterial enhancement, and time‐to‐peak portal enhancement on CTA between sedated healthy control cats and those with chronic DM. Results The pancreas in cats with chronic DM was significantly larger, had higher volume, higher V:BW, and shorter time‐to‐peak portal enhancement on CTA when compared to normal cats. Conclusions and Clinical Importance Peak portal enhancement time, pancreatic size, pancreatic volume, and V:BW can be used to differentiate normal sedated cats from those with chronic DM by CTA. These variables warrant further investigation to identify possible associations with endocrine function. |
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Keywords: | Contrast Endocrine Feline Iodinated |
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