A field experiment was conducted to study effects of different combination of nitrogen and phosphorus application on one-year old Aloe under 30; sea water irrigation. Regression equation of the leaf yield to the amounts of nitrogen and phosphorus application was estimated. The results obtained showed that the maximum leaf yield of Aloe was obtained within the nitrogen supply amount of N2 to N; and phosphorus of P2 to P;. Over application of nitrogen and phosphorus fertilizers can result in a decreasing trend in the leaf yield. The maximum leaf yield of 26 015 kg/hm^2 calculated from the regression equation occurred when the application amounts of nitrogen and phosphorus reached 141.9 kg/hm^2 and 84.0 kg/hm^2, respectively. At the same rate of phosphorus, the single leaf weight of Aloe was increased with the increase of N application, while the greatest single leaf weight of Aloe was found within the phosphorus supply of P2 to P; when the same amount of N fertilizer was applied. Compared to CK, anthraquinon content in the mature leaf was increased by combined application of N and P fertilizers, with the greatest increases by 23 ; at N;P2. The co-provision of N and P fertilizer helped to increase the leaf Anthraquinon content in leaf. In comparison of the sole application of N, Anthraquinon content was greater in the plants supplied with both N and P fertilizers. Aloin contents in leaves were increased by 5% to 132% at the different combinations of N and P fertilizers. The greatest aloin content occurred at N; and was significantly greater than that of No, N; and N4, irrespective of the application amount of phosphorus. Increasing of application was propitious for improving Aaloin content in leaf at low supply rate of N.