In order to verify the application effect of the “big recipe， small adjustment” recipe technology on winter wheat， a field experiment， including farmers’ custom formulas(15-15-15， 25-12-8)， regional large formula(15-20-10， 18-15-12) and small adjusted formula(20-15-10， 22-16-7)， was conducted in Linying County， Henan Province to analysze effects of different formula fertilizers on wheat population， dry matter accumulation， nutrients absorption， stress resistance， grain yield， economic benefits， etc.The results showed that the community number of high-nitrogen formula 25-12-8 in the farmers’ custom formula was higher， and the SPAD value was higher in the early stage than in other formulas， but lower in the later growth stages.Small adjusted formula 20-15-10 had the highest dry matter accumulation during wheat maturity， while farmers’ fertilizer formulas 25-12-8 and 15-15-15 were lower； and the rate of assimilation after flowering contributing to the grain was the highest in formula 20-15-10.Small adjusted formula 20-15-10 had a relatively high nitrogen， phosphorus and potassium nutrient accumulation， which was second to the large formula 18-15-12.Judging from the incidence of scab and frost damage， the incidence of scab and frost damage under the small formula 20-15-10 was the smallest， which was 9.3% and 2.0%， respectively. Compared with other formulas， the harvest index of the small adjusted formula 20-15-10 was significantly improved， and its grain yield was the highest， which increased by 18.4% over the farmers’ custom formula 15-15-15.The treatment with both highest partial productivity of nitrogen fertilizer and phosphate fertilizer was small formula 20-15-10， and the partial productivity of potassium fertilizer was second to the largest formula 22-16-7.From the perspective of economic benefits， the net income among the formulas ranked as 20-15-10>18-15-12>22-16-7>25-12-8>15-20-10>15-15-15.Taken together， the small adjusted formula 20-15-10， which was adjusted according to crop nutrient requirements and soil conditions， can improve the dry matter and nutrient accumulation， stress resistance， economic benefits and fertilizer utilization of winter wheat.“big recips，smau adjustment” can achieve increased production， income and efficiency.