Abstract: With improvement of level of e-commerce development，logistics industry has also made great progress.The cold chain logistics distribution mode of fresh agricultural products is becoming more and more perfect，which has a positive impact on trading activities of fresh agricultural products.There are still some problems in cold-chain logistics distribution of fresh agricultural products，such as weak infrastructure and unscrupulous professionalism，which seriously restrict system optimization of cold-chain logistics distribution.Suggestions were put forward for development of cold-chain logistics distribution mode of fresh agricultural products in order to provide scientific guidance for optimization of other distribution modes.